The MTMR8 Polyclonal Antibody (CAB17723) is a vital tool for researchers studying the MTMR8 protein, which plays a crucial role in cellular functions such as signaling pathways and membrane trafficking. This antibody, derived from rabbit hosts, exhibits high specificity and sensitivity for human samples, making it a reliable tool for Western blot analyses.MTMR8 is a phosphatase enzyme involved in the regulation of cell growth, differentiation, and survival. Dysregulation of MTMR8 has been implicated in various diseases, including cancer and neurodegenerative disorders.
By targeting the MTMR8 protein, researchers can gain valuable insights into its role in disease development and progression.With its ability to specifically bind to MTMR8, this polyclonal antibody enables researchers to accurately detect and analyze the protein in different cell types and tissues. Its applications extend to studies in cell biology, cancer research, and neurodegenerative diseases, making it an essential tool for investigating the molecular mechanisms underlying these conditions.
Product Name:
MTMR8 Rabbit Polyclonal Antibody
SKU:
CAB17723
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 430-560 of human MTMR8 (NP_060147.2).
This gene encodes a member of the myotubularin-related family and is part of the MTMR6 subgroup. Family members are dual-specificity phosphatases and the encoded protein contains a phosphoinositide-binding domain (PID) and a SET-interacting domain (SID). Defects in other family members have been found in myotubular myopathic diseases.
Purification Method:
Affinity purification
Gene ID:
55613
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MTMR8 Rabbit pAb (CAB17723) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
