The MTMR11 Polyclonal Antibody (PAC028426) is a valuable tool for researchers studying the MTMR11 protein, a phosphoinositide phosphatase involved in regulating cellular processes such as autophagy and endocytic trafficking. This antibody, produced in rabbits, has high specificity for human samples and has been validated for use in Western blot applications. By binding to the MTMR11 protein, this antibody allows for the detection and analysis of MTMR11 levels in various cell types, making it ideal for studies in cell biology and cancer research.MTMR11 is known to play a role in the regulation of autophagy, a cellular process that is crucial for maintaining cellular homeostasis and responding to various stress conditions.
Dysregulation of autophagy has been linked to the development of cancer and neurodegenerative disorders, highlighting the importance of studying MTMR11 in these contexts. By using the MTMR11 Polyclonal Antibody, researchers can further elucidate the functions of MTMR11 and its potential implications in disease pathogenesis, paving the way for new therapeutic strategies targeting this key regulatory protein.
Antibody Name:
MTMR11 Antibody (PACO28426)
Antibody SKU:
PACO28426
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human Myotubularin-related protein 11 protein (1-240AA)
Probable pseudophosphatase. Contains a Glu residue instead of a conserved Cys residue in the dsPTPase catalytic loop which renders it catalytically inactive as a phosphatase (Potential).
Synonyms:
Myotubularin-related protein 11 (Cisplatin resistance-associated protein) (hCRA), MTMR11
UniProt Protein Function:
MTMR11: Probable pseudophosphatase. Contains a Glu residue instead of a conserved Cys residue in the dsPTPase catalytic loop which renders it catalytically inactive as a phosphatase (Potential). Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily. 6 isoforms of the human protein are produced by alternative splicing.Protein type: Protein phosphatase, tyrosine (non-receptor)Chromosomal Location of Human Ortholog: 1q21.2
