The Myotubularin Polyclonal Antibody (CAB0255) is a valuable tool for researchers studying the myotubularin protein, which plays a crucial role in various cellular processes related to muscle development and function. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.Myotubularin is a phosphoinositide phosphatase involved in the regulation of membrane trafficking and signaling pathways within cells. Dysregulation of myotubularin has been linked to various neuromuscular disorders, making it a promising target for therapeutic interventions.
By using the Myotubularin Polyclonal Antibody, researchers can effectively detect and analyze the expression of myotubularin in different cell types, providing valuable insights into its functions and potential implications in disease states. This antibody is a valuable tool for advancing research in muscle biology, neuromuscular diseases, and drug discovery efforts targeting myotubularin-related pathways.
Product Name:
MTM1 Rabbit Polyclonal Antibody
SKU:
CAB0255
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 484-603 of human MTM1 (NP_000243.1).
This gene encodes a dual-specificity phosphatase that acts on both phosphotyrosine and phosphoserine. It is required for muscle cell differentiation and mutations in this gene have been identified as being responsible for X-linked myotubular myopathy.
Purification Method:
Affinity purification
Gene ID:
4534
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MTM1 antibody (CAB0255) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
