The MTIF3 Polyclonal Antibody (CAB8524) is a versatile tool for researchers studying MTIF3, a protein involved in mitochondrial translation initiation. This antibody, generated in rabbits, has high specificity for human samples and has been validated for use in Western blot applications. By targeting the MTIF3 protein, this antibody allows for the detection and analysis of MTIF3 in a variety of cell types, making it well-suited for research in molecular biology and mitochondrial function.MTIF3 plays a crucial role in the initiation of protein synthesis within the mitochondria, a process essential for proper cellular function and energy production.
Dysregulation of mitochondrial translation initiation has been linked to various diseases, including metabolic disorders and neurodegenerative conditions. By studying the function of MTIF3, researchers can gain insights into these pathologies and potentially identify new therapeutic targets for intervention.Overall, the MTIF3 Polyclonal Antibody offers researchers a valuable tool for investigating the role of MTIF3 in mitochondrial translation and its implications for human health and disease.
Product Name:
MTIF3 Rabbit Polyclonal Antibody
SKU:
CAB8524
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-278 of human MTIF3 (NP_690876.3).
This gene encodes a translation initiation factor that is involved in mitochondrial protein synthesis. Polymorphism in this gene is associated with the onset of Parkinson's disease. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.
Purification Method:
Affinity purification
Gene ID:
219402
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MTIF3 antibody (CAB8524) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
