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MTHFR Rabbit Polyclonal Antibody (CAB0305)

SKU:
CAB0305
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:MTHFR Rabbit Polyclonal Antibody
SKU:CAB0305
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human MTHFR (NP_005948.3).
Sequence:MVNE ARGN SSLN PCLE GSAS SGSE SSKD SSRC STPG LDPE RHER LREK MRRR LESG DKWF SLEF FPPR TAEG AVNL ISRF DRMA AGGP LYID VTWH PAGD PGSD KETS SMMI ASTA VNYC GLET ILHM TCCR QRLE EITG HLHK AKQL GLKN IMAL RGDP IGDQ WEEE EGGF NYAV DLVK HIRS EFGD YFDI CVAG YPKG HPEA GSFE ADLK HLKE KVSA GADF IITQ LF
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:MTHFR
Positive Sample:Rat kidney
Conjugate:Unconjugated
Cellular Localization:cytosol, synapse
Calculated MW:75kDa
Observed MW:75kDa

The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.

Purification Method:Affinity purification
Gene ID:4524
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of Rat kidney, using MTHFR Rabbit pAb (CAB0305) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

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