The MTHFR Rabbit Polyclonal Antibody offered by AssayGenie is a valuable tool for researchers studying the methylenetetrahydrofolate reductase (MTHFR) enzyme. This antibody is designed to specifically target and detect the MTHFR protein in human samples, providing accurate and reliable results for Western blot applications.MTHFR is an essential enzyme involved in the metabolism of folate and homocysteine, making it a key player in various physiological processes, including DNA synthesis and repair. Mutations in the MTHFR gene have been linked to a range of health conditions, such as cardiovascular disease, neural tube defects, and certain types of cancer.
By using the MTHFR Rabbit Polyclonal Antibody, researchers can gain insights into the role of MTHFR in health and disease, paving the way for the development of targeted therapies and personalized treatments. Its high reactivity and specificity make it a valuable asset for studies in genetics, biochemistry, and molecular biology. Unlock the secrets of MTHFR with this powerful research tool from AssayGenie.
Product Name:
MTHFR Rabbit Polyclonal Antibody
SKU:
CAB0305
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human MTHFR (NP_005948.3).
The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
Purification Method:
Affinity purification
Gene ID:
4524
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of Rat kidney, using MTHFR Rabbit pAb (CAB0305) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
