MTHFD2 Rabbit Polyclonal Antibody (CAB10386)
- SKU:
- CAB10386
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | MTHFD2 Rabbit Polyclonal Antibody |
SKU: | CAB10386 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-250 of human MTHFD2 (NP_006627.2). |
Sequence: | ISGR KLAQ QIKQ EVRQ EVEE WVAS GNKR PHLS VILV GENP ASHS YVLN KTRA AAVV GINS ETIM KPAS ISEE ELLN LINK LNND DNVD GLLV QLPL PEHI DERR ICNA VSPD KDVD GFHV INVG RMCL DQYS MLPA TPWG VWEI IKRT GIPT LGKN VVVA GRSK NVGM PIAM LLHT DGAH ERPG GDAT VTIS HRYT PKEQ LKKH TILA DIV |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | NMDMC; MTHFD2 |
Positive Sample: | 293T,LO2,Jurkat,HeLa,Mouse spleen,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion. |
Calculated MW: | 38kDa |
Observed MW: | 38kDa |
This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.
Purification Method: | Affinity purification |
Gene ID: | 10797 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |