The MTHFD1L Polyclonal Antibody (CAB7969) is a valuable tool for researchers studying MTHFD1L, a key enzyme involved in folate metabolism and one-carbon metabolism pathways. This antibody, generated in rabbits, exhibits high specificity and reactivity towards the human MTHFD1L protein, making it ideal for use in Western blot experiments.MTHFD1L is crucial for the synthesis of purines and pyrimidines, essential building blocks for DNA and RNA production. Dysregulation of MTHFD1L has been linked to various diseases, including cancer, cardiovascular disorders, and neural tube defects.
By targeting MTHFD1L with this polyclonal antibody, researchers can investigate its role in disease progression and potentially identify new therapeutic targets.With its ability to detect MTHFD1L in a variety of cell types, this antibody is a valuable tool for scientists conducting research in fields such as cancer biology, developmental biology, and metabolism. By unraveling the intricacies of MTHFD1L function, researchers can gain deeper insights into the molecular mechanisms underlying disease pathology, paving the way for the development of novel therapeutic strategies.
Product Name:
MTHFD1L Rabbit Polyclonal Antibody
SKU:
CAB7969
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 759-978 of human MTHFD1L (NP_056255.2).
The protein encoded by this gene is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. THF is important in the de novo synthesis of purines and thymidylate and in the regeneration of methionine from homocysteine. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
25902
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using MTHFD1L Rabbit pAb (CAB7969) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
