MTHFD1 Rabbit Polyclonal Antibody (CAB8661)
- SKU:
- CAB8661
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | MTHFD1 Rabbit Polyclonal Antibody |
SKU: | CAB8661 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human MTHFD1 (NP_005947.3). |
Sequence: | MAPA EILN GKEI SAQI RARL KNQV TQLK EQVP GFTP RLAI LQVG NRDD SNLY INVK LKAA EEIG IKAT HIKL PRTT TESE VMKY ITSL NEDS TVHG FLVQ LPLD SENS INTE EVIN AIAP EKDV DGLT SINA GKLA RGDL NDCF IPCT PKGC LELI KETG VPIA GRHA VVVG RSKI VGAP MHDL LLWN NATV TTCH SKTA HLDE EVNK GDIL VVAT GQPE MVKG EWIK PGAI VIDC GINY VPDD KKPN GRKV VGDV AYDE AKER ASFI TP |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | CIMAH; MTHFC; MTHFD; MTHFD1 |
Positive Sample: | Raji,LO2,Mouse brain,Mouse kidney,Rat spinal cord |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 102kDa |
Observed MW: | 115kDa |
This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain.
Purification Method: | Affinity purification |
Gene ID: | 4522 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |