The MTG2 Polyclonal Antibody (PACO3818) is a valuable tool for researchers studying the MTG2 protein, which is involved in a variety of cellular processes including transcriptional regulation and apoptosis. This antibody, produced in rabbits, exhibits high specificity for human samples and has been validated for use in Western blotting applications. By targeting the MTG2 protein, this antibody allows for the detection and analysis of MTG2 expression in different cell types, making it well-suited for investigations in the fields of molecular biology and cancer research.MTG2, also known as myeloid translocation gene 8, plays a crucial role in regulating gene expression and cell survival.
Dysregulation of MTG2 has been linked to various disease states, including cancer and developmental disorders. By studying the function of MTG2 with this antibody, researchers can gain insights into its role in these conditions and potentially uncover new targets for therapeutic intervention. The MTG2 Polyclonal Antibody is a valuable asset for understanding the complexities of cellular processes involving MTG2 and advancing our knowledge of disease mechanisms.
Antibody Name:
MTG2 Antibody
Antibody SKU:
PACO03818
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
IHC:1:100-1:300
Species Reactivity:
Human, Mouse, Rat
Immunogen:
synthesized peptide derived from the Internal region of human GTPBP5.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
GTPBP5; OBGH1; GTP-binding protein 5; Protein obg homolog 1; ObgH1
UniProt Protein Function:
MTG2: Involved in the ribosome maturation process. Plays a role of GTPase in vitro. When missing, mitochondria elongation and abnormal nuclear morphology are observed. Belongs to the GTP1/OBG family.Chromosomal Location of Human Ortholog: 20q13.33Cellular Component: mitochondrial inner membrane; mitochondrial matrix; mitochondrial ribosomeMolecular Function: GTPase activity
UniProt Protein Details:
NCBI Summary:
Small G proteins, such as GTPBP5, act as molecular switches that play crucial roles in the regulation of fundamental cellular processes such as protein synthesis, nuclear transport, membrane trafficking, and signal transduction (Hirano et al., 2006 [PubMed 17054726]).[supplied by OMIM, Mar 2008]
