The MTCO2 Rabbit Monoclonal Antibody (CAB3843) is specifically designed for research involving the MTCO2 protein, a critical component of the mitochondrial respiratory chain. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blot and immunohistochemistry.The MTCO2 protein plays a crucial role in cellular respiration by facilitating the transfer of electrons within the mitochondrial complex IV. Dysregulation of MTCO2 has been implicated in various metabolic disorders, neurodegenerative diseases, and cancer. Therefore, the MTCO2 Rabbit Monoclonal Antibody is an invaluable tool for studying mitochondrial function and exploring potential therapeutic targets in these pathologies.
Researchers in the fields of biochemistry, cell biology, and medicine will find this antibody particularly useful for investigating the role of MTCO2 in mitochondrial dysfunction and its implications for human health. By enabling accurate detection and analysis of MTCO2 expression in different cell types, this antibody facilitates in-depth studies that contribute to our understanding of mitochondrial biology and disease mechanisms.
Product Name:
MTCO2 Rabbit Monoclonal Antibody
SKU:
CAB3843
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 128-227 of human MTCO2 (P00403).
Contributes to cytochrome-c oxidase activity. Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen and positive regulation of vasoconstriction. Located in mitochondrial inner membrane. Part of respiratory chain complex IV. Biomarker of Huntington's disease and stomach cancer.
Purification Method:
Affinity purification
Gene ID:
4513
Clone Number:
ARC0844
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using MTCO2 Rabbit mAb (CAB3843) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
