The MTCO1 Polyclonal Antibody (CAB17889) is ideal for research involving the MTCO1 protein, which is a subunit of cytochrome c oxidase (COX) involved in the electron transport chain of oxidative phosphorylation. This antibody, raised in rabbits, displays high reactivity with human samples and is suitable for use in Western blot applications.The MTCO1 protein plays a crucial role in mitochondrial function and energy production, making it a key target for studies in areas such as metabolism, aging, and neurodegenerative diseases. By detecting and analyzing the MTCO1 protein in various cell types, this antibody enables researchers to explore the role of COX subunits in cellular respiration and mitochondrial dysfunction.
Understanding the function of MTCO1 is essential for unraveling the mechanisms underlying mitochondrial disorders and metabolic diseases. By utilizing this polyclonal antibody in their research, scientists can further investigate the impact of MTCO1 on cellular bioenergetics and explore potential therapeutic interventions targeting mitochondrial dysfunction.
Product Name:
MTCO1 Rabbit Polyclonal Antibody
SKU:
CAB17889
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 400-500 of human MTCO1 (YP_002124304.1).
mitochondrial inner membrane, mitochondrial respiratory chain complex III, mitochondrial respiratory chain complex IV
Calculated MW:
57kDa
Observed MW:
40kDa/37kDa
Contributes to cytochrome-c oxidase activity. Predicted to be involved in electron transport coupled proton transport and mitochondrial electron transport, cytochrome c to oxygen. Part of mitochondrial respiratory chain complex III and mitochondrial respiratory chain complex IV.
Purification Method:
Affinity purification
Gene ID:
4512
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MTCO1 antibody (CAB17889) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
