The MTAP Polyclonal Antibody is a powerful tool for researchers studying the MTAP protein, a key enzyme involved in the metabolism of purine and methionine. This antibody, produced in rabbits, offers high specificity and sensitivity for detecting MTAP in human samples, making it ideal for use in Western blotting, immunohistochemistry, and other research applications.MTAP plays a critical role in cell metabolism, influencing processes such as DNA synthesis and repair. Dysregulation of MTAP has been linked to various cancers, making it a promising target for cancer research and drug development.
By using the MTAP Polyclonal Antibody, researchers can gain valuable insights into the function of this important enzyme and its potential role in disease pathogenesis.Overall, the MTAP Polyclonal Antibody from Assay Genie provides researchers with a reliable tool for studying the biology of MTAP and its implications in health and disease. With its high specificity and versatility, this antibody is a valuable asset for any laboratory conducting research in the fields of cancer biology, metabolism, and molecular biology.
Product Name:
MTAP Polyclonal Antibody
SKU:
CAB21496
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-283 of human MTAP (NP_002442.2).
This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage pathway of both adenine and methionine. The encoded enzyme is deficient in many cancers. Multiple alternatively spliced transcript variants have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
4507
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using MTAP Rabbit pAb (CAB21496) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
