The MTAP Monoclonal Antibody (CAB22045) is a valuable tool for researchers studying MTAP, a key enzyme involved in the methionine salvage pathway. This antibody, produced using a monoclonal antibody technology, offers high specificity and sensitivity for detecting MTAP protein in various biological samples.MTAP plays a crucial role in regulating cellular methionine metabolism and has been implicated in cancer progression and drug resistance. By targeting MTAP with this antibody, researchers can better understand its function and potential therapeutic implications in cancer treatment. The antibody is suitable for use in applications such as Western blotting, immunofluorescence, and immunohistochemistry, allowing for detailed analysis of MTAP expression in different cellular contexts.
This MTAP Monoclonal Antibody is an essential tool for scientists investigating the role of MTAP in cancer biology and developing targeted therapies for MTAP-related diseases. Its high specificity and sensitivity make it a reliable option for detecting and quantifying MTAP protein levels, providing valuable insights into the complex mechanisms of methionine metabolism and its impact on cancer development.
Product Name:
MTAP Monoclonal Antibody
SKU:
CAB22045
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-283 of human MTAP (NP_002442.2).
This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage pathway of both adenine and methionine. The encoded enzyme is deficient in many cancers. Multiple alternatively spliced transcript variants have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
4507
Clone Number:
ARC54717
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MTAP antibody (CAB22045) at1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
