The MT1G Polyclonal Antibody (PAC033808) is a valuable tool for research involving MT1G, a gene involved in the regulation of various cellular processes, including detoxification and antioxidant defense mechanisms. This rabbit-raised antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding to the MT1G protein, researchers can easily detect and analyze its expression in different cell types, making it a versatile tool for studies in toxicology, cancer research, and oxidative stress-related diseases.MT1G is a critical player in cellular protection against toxic compounds and oxidative stress, making it a key target in understanding the mechanisms underlying various diseases, such as cancer and neurodegenerative disorders.
By elucidating the role of MT1G in these pathological conditions, researchers can potentially identify new therapeutic strategies aimed at enhancing detoxification pathways and reducing oxidative damage within cells. In summary, the MT1G Polyclonal Antibody is an essential asset for research aimed at unraveling the complex functions of MT1G in health and disease, providing valuable insights into potential therapeutic interventions for a range of pathological conditions.
Antibody Name:
MT1G Antibody (PACO33808)
Antibody SKU:
PACO33808
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Metallothionein-1G protein (1-59AA)
Immunohistochemistry of paraffin-embedded human colon cancer using PACO33808 at dilution of 1: 100.
Background:
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
MT1G: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. Belongs to the metallothionein superfamily. Type 1 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: CarrierChromosomal Location of Human Ortholog: 16q13Cellular Component: cytoplasm; nucleus; perinuclear region of cytoplasmMolecular Function: protein binding; zinc ion bindingBiological Process: monocyte activation; monocyte differentiation; negative regulation of growth; response to metal ion