MT1E Antibody (PACO33800)
- SKU:
- PACO33800
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
MT1E Antibody (PACO33800)
The MT1E Polyclonal Antibody (PAC033800) is a valuable tool for researchers studying the MT1E protein, a key player in metallothionein-mediated heavy metal detoxification and protection against oxidative stress. This antibody, generated in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By targeting the MT1E protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential tool for studies in toxicology, environmental health, and cancer research.MT1E, a member of the metallothionein family, is known for its role in binding heavy metals such as cadmium, copper, and zinc, preventing their harmful effects on cells.
Its ability to scavenge free radicals and regulate metal ion homeostasis makes it a promising target for investigating metal-induced toxicity, as well as potential therapeutic strategies for conditions related to heavy metal exposure. Understanding the function of MT1E is crucial for advancing our knowledge of metal detoxification mechanisms and developing interventions to mitigate metal-related health risks.
| Antibody Name: | MT1E Antibody (PACO33800) |
| Antibody SKU: | PACO33800 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:10-1:100, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Metallothionein-1E protein (4-59AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO33800 at dilution of 1:20. |
 | Immunofluorescent analysis of HepG2 cells using PACO33800 at dilution of 1:100. |
| Background: | Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. |
| Synonyms: | Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE), MT1E |
| UniProt Protein Function: | MT1E: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. Belongs to the metallothionein superfamily. Type 1 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Carrier Chromosomal Location of Human Ortholog: 16q13 Cellular Component: perinuclear region of cytoplasm; cytoplasm; nucleus Molecular Function:zinc ion binding Biological Process: negative regulation of growth |
| UniProt Code: | P04732 |
| NCBI GenInfo Identifier: | 83367075 |
| NCBI Gene ID: | 4493 |
| NCBI Accession: | NP_783316.2 |
| UniProt Secondary Accession: | P04732,Q86YX4, Q8TD51, A2RRF7, |
| UniProt Related Accession: | P04732 |
| Molecular Weight: | 6,014 Da |
| NCBI Full Name: | metallothionein-1E |
| NCBI Synonym Full Names: | metallothionein 1E |
| NCBI Official Symbol: | MT1EÂ Â |
| NCBI Official Synonym Symbols: | MT1; MTDÂ Â |
| NCBI Protein Information: | metallothionein-1E; MT-1E; MT-IE; metallothionein D; metallothionein-IE; metallothionein 1E (functional) |
| UniProt Protein Name: | Metallothionein-1E |
| UniProt Synonym Protein Names: | Metallothionein-IE |
| Protein Family: | Metallothionein |
| UniProt Gene Name: | MT1EÂ Â |
| UniProt Entry Name: | MT1E_HUMAN |
| ELISA Kits |
| Human MT1E / Metallothionein-1E ELISA Kit |
| Human MT1E (Metallothionein 1E) CLIA Kit (HUES00399) |
| Human MT1E (Metallothionein 1E) ELISA Kit (HUES01766) |
| Human Metallothionein-1E (MT1E) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
Human Metallothionein-1E (MT1E) ELISA Kit (HUEB0528)
Human Metallothionein 1E (MT1E) ELISA Kit
Porcine Metallothionein-1E (MT1E) ELISA Kit (PREB0091)
