The MT-ND4L Rabbit Polyclonal Antibody (CAB17971) is a research tool designed for the study of the MT-ND4L protein, a key component of the mitochondrial electron transport chain. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.MT-ND4L, also known as NADH-ubiquinone oxidoreductase chain 4L, plays a critical role in the generation of cellular energy through oxidative phosphorylation. Dysregulation of this protein has been implicated in various diseases, including mitochondrial disorders and metabolic syndromes.
By targeting the MT-ND4L protein, researchers can investigate its function in cellular metabolism and energy production, offering insights into potential therapeutic strategies for related disorders.This antibody enables the detection and analysis of MT-ND4L in diverse cell types, making it a valuable tool for studies in mitochondrial biology, metabolism, and related fields. Its specificity and sensitivity make it an ideal choice for researchers seeking to further understand the role of MT-ND4L in health and disease.
Product Name:
MT-ND4L Rabbit Polyclonal Antibody
SKU:
CAB17971
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 40 to the C-terminus of human MT-ND4L (AXQ02532.1).
mitochondrial inner membrane, mitochondrial respiratory chain complex I
Calculated MW:
11kDa
Observed MW:
11kDa
Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be located in mitochondrial inner membrane. Implicated in Leber hereditary optic neuropathy and diabetes mellitus.
Purification Method:
Affinity purification
Gene ID:
4539
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using MT-ND4L Rabbit pAb (CAB17971) at 1:600 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
