The MT-ND4 Polyclonal Antibody (CAB9941) is a valuable tool for researchers studying the mitochondrial protein ND4, which is involved in electron transport and ATP synthesis in the respiratory chain. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the MT-ND4 protein, this antibody allows for accurate detection and analysis in a variety of cell types.MT-ND4 is a key player in mitochondrial function, making it a crucial target for research in areas such as bioenergetics, aging, and neurodegenerative diseases.
Understanding the role of MT-ND4 in the mitochondria is essential for uncovering its potential implications in various health conditions and developing targeted therapies. The MT-ND4 Polyclonal Antibody offers researchers a reliable tool for investigating the function and regulation of this critical mitochondrial protein.
Product Name:
MT-ND4 Rabbit Polyclonal Antibody
SKU:
CAB9941
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 360-459 of mouse MT-ND4 (NP_904337.1).
Predicted to enable NADH dehydrogenase (ubiquinone) activity and ubiquinone binding activity. Predicted to contribute to NADH dehydrogenase activity. Predicted to be involved in several processes, including electron transport coupled proton transport; mitochondrial electron transport, NADH to ubiquinone; and mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; Parkinson's disease; macular degeneration; and schizophrenia. Orthologous to human MT-ND4 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4).
Purification Method:
Affinity purification
Gene ID:
17719
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MT-ND4 antibody (CAB9941) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
