The MT-ND3 Polyclonal Antibody (CAB9940) is a valuable tool for researchers studying the MT-ND3 protein, a subunit of the mitochondrial respiratory chain complex I. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the MT-ND3 protein, this antibody enables precise detection and analysis of mitochondrial function in a variety of cell types.The MT-ND3 protein is crucial for energy production in the cell, making it a key player in cellular metabolism and function. Dysregulation of mitochondrial function, including the MT-ND3 protein, has been implicated in a variety of diseases, including neurodegenerative disorders and metabolic diseases.
By studying the MT-ND3 protein, researchers can gain insights into mitochondrial function and its role in health and disease.Overall, the MT-ND3 Polyclonal Antibody is a valuable tool for researchers interested in studying mitochondrial function and its implications for human health. Its high specificity and sensitivity make it an ideal choice for studies in biochemistry, cell biology, and disease research.
Product Name:
MT-ND3 Rabbit Polyclonal Antibody
SKU:
CAB9940
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of mouse MT-ND3 (NP_904335.1).
Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in cellular response to glucocorticoid stimulus; mitochondrial electron transport, NADH to ubiquinone; and response to oxidative stress. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; Leigh disease; and Parkinson's disease. Orthologous to human MT-ND3 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3).
Purification Method:
Affinity purification
Gene ID:
17718
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MT-ND3 Antibody (CAB9940) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
