The MT-ND2 Polyclonal Antibody (CAB17968) is a valuable tool for researchers studying the MT-ND2 protein, an essential component of the mitochondrial respiratory chain. This antibody, derived from rabbit serum, exhibits high specificity and sensitivity when detecting MT-ND2 in human samples, making it ideal for use in Western blot applications. By targeting the MT-ND2 protein, this antibody allows for the accurate identification and analysis of mitochondrial function in various cell types.The MT-ND2 protein is involved in the electron transport chain within mitochondria, playing a crucial role in energy production and cellular metabolism. Dysregulation of MT-ND2 has been linked to a variety of diseases, including neurodegenerative disorders and metabolic conditions.
By investigating the expression and activity of MT-ND2 using this antibody, researchers can gain valuable insights into the mechanisms underlying these pathologies and identify potential therapeutic targets.Overall, the MT-ND2 Polyclonal Antibody (CAB17968) serves as a valuable tool for studying mitochondrial function and its implications for human health. Its high reactivity and specificity make it a reliable choice for researchers conducting studies in areas such as metabolism, aging, and mitochondrial-related diseases.
Product Name:
MT-ND2 Rabbit Polyclonal Antibody
SKU:
CAB17968
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 248-347 of human MT-ND2 (YP_003024027.1).
mitochondrial inner membrane, mitochondrial respiratory chain complex I
Calculated MW:
39kDa
Observed MW:
39kDa
Enables NADH dehydrogenase (ubiquinone) activity. Involved in mitochondrial electron transport, NADH to ubiquinone and mitochondrial respiratory chain complex I assembly. Part of mitochondrial respiratory chain complex I. Implicated in Leber hereditary optic neuropathy; multiple sclerosis; myocardial infarction; neurodegenerative disease (multiple); and urinary bladder cancer.
Purification Method:
Affinity purification
Gene ID:
4536
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using MT-ND2 Rabbit pAb (CAB17968) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
