The MT-CYB Polyclonal Antibody (CAB17966) is a valuable tool for researchers studying the MT-CYB protein, a key component of the electron transport chain in mitochondria. This rabbit polyclonal antibody is highly reactive with human samples and is validated for use in Western blot applications. By specifically binding to the MT-CYB protein, this antibody allows for accurate detection and analysis in various cell types, making it an ideal choice for studies in mitochondrial biology and related fields.
MT-CYB is essential for electron transfer during oxidative phosphorylation, making it crucial for ATP production and cellular energy metabolism. Dysregulation of MT-CYB has been linked to various diseases, including mitochondrial disorders and cancer. Research into the function and regulation of MT-CYB is important for understanding the role of mitochondria in health and disease, and may lead to the development of targeted therapies for mitochondrial dysfunction-related conditions.
Product Name:
MT-CYB Rabbit Polyclonal Antibody
SKU:
CAB17966
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human MT-CYB (YP_003024038.1).
mitochondrial inner membrane, mitochondrial respiratory chain complex III, mitochondrion
Calculated MW:
43kDa
Observed MW:
43kDa
Predicted to enable metal ion binding activity. Predicted to be involved in several processes, including electron transport coupled proton transport; response to cobalamin; and response to glucagon. Located in mitochondrion. Implicated in ovarian carcinoma and urinary bladder cancer.
Purification Method:
Affinity purification
Gene ID:
4519
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MT-CYB Rabbit pAb (CAB17966) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
