The MT-CO3 Polyclonal Antibody (CAB9939) is an essential tool for researchers studying mitochondrial function and oxidative phosphorylation. This antibody, generated in rabbits, is highly specific to the MT-CO3 protein and is validated for use in various applications including Western blotting and immunohistochemistry.MT-CO3, a subunit of cytochrome c oxidase (Complex IV) in the electron transport chain, plays a crucial role in mitochondrial respiration and ATP production. Dysregulation of MT-CO3 has been linked to mitochondrial dysfunction, oxidative stress, and various metabolic disorders.
By targeting MT-CO3, researchers can gain insights into mitochondrial function and its impact on cellular processes.The MT-CO3 Polyclonal Antibody is an invaluable tool for investigating mitochondrial biology, bioenergetics, and the role of oxidative phosphorylation in health and disease. Its high specificity and sensitivity make it ideal for studying mitochondrial function in a wide range of cell types and tissues. Unlock the potential of your research with the MT-CO3 Polyclonal Antibody (CAB9939).
Product Name:
MT-CO3 Rabbit Polyclonal Antibody
SKU:
CAB9939
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of mouse MT-CO3 (NP_904334.1).
Predicted to enable electron transfer activity and oxidoreduction-driven active transmembrane transporter activity. Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen and respiratory chain complex IV assembly. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; heart; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in MELAS syndrome. Orthologous to human MT-CO3 (mitochondrially encoded cytochrome c oxidase III).
Purification Method:
Affinity purification
Gene ID:
17710
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MT-CO3 antibody (CAB9939) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
