The MT-CO3 Polyclonal Antibody (CAB17891) is specially designed for researchers studying the MT-CO3 protein, a crucial component of the mitochondrial respiratory chain. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the MT-CO3 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an excellent tool for investigations in the fields of mitochondrial biology and metabolic disorders.MT-CO3, also known as cytochrome c oxidase III, is essential for the function of complex IV in the respiratory chain, playing a key role in energy production within the mitochondria.
Dysregulation of MT-CO3 has been implicated in a range of diseases, including mitochondrial disorders, neurodegenerative conditions, and metabolic syndromes. Research on MT-CO3 is crucial for enhancing our understanding of mitochondrial function and its impact on human health, potentially leading to the development of novel therapeutic strategies for mitochondrial-related diseases.
Product Name:
MT-CO3 Rabbit Polyclonal Antibody
SKU:
CAB17891
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MT-CO3 (YP_003024032.1).
mitochondrial inner membrane, mitochondrial respiratory chain complex IV, mitochondrion
Calculated MW:
30kDa
Observed MW:
30kDa
Predicted to enable electron transfer activity and oxidoreduction-driven active transmembrane transporter activity. Involved in respiratory chain complex IV assembly. Part of respiratory chain complex IV. Implicated in MELAS syndrome.
Purification Method:
Affinity purification
Gene ID:
4514
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse kidney, using MT-CO3 Rabbit pAb (CAB17891) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
