The MT-CO2 Polyclonal Antibody (CAB17965) is a crucial tool for researchers studying mitochondrial complex IV subunit 2 (MT-CO2), a key component of the respiratory chain involved in energy production within cells. This rabbit polyclonal antibody is highly specific to human samples and has been validated for use in Western blot applications.MT-CO2 is essential for the proper functioning of mitochondria and plays a crucial role in cellular respiration. Dysregulation of MT-CO2 has been implicated in various diseases, including metabolic disorders, neurodegenerative conditions, and cancer.
By targeting MT-CO2 with this antibody, researchers can investigate its expression levels and activity in different cell types, shedding light on its role in health and disease.With its high reactivity and specificity, the MT-CO2 Polyclonal Antibody is an invaluable tool for studies in mitochondrial biology, biochemistry, and disease mechanisms. By enabling the detection and analysis of MT-CO2 protein, this antibody can contribute to our understanding of mitochondrial function and its implications for human health.
Product Name:
MTCO2 Rabbit Polyclonal Antibody
SKU:
CAB17965
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 40-100 of human MTCO2 (YP_003024029.1).
Sequence:
YALF LTLT TKLT NTNI SDAQ EMET VWTI LPAI ILVL IALP SLRI LYMT DEVN DPSL TIKS I
Contributes to cytochrome-c oxidase activity. Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen and positive regulation of vasoconstriction. Located in mitochondrial inner membrane. Part of respiratory chain complex IV. Biomarker of Huntington's disease and stomach cancer.
Purification Method:
Affinity purification
Gene ID:
4513
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of HeLa, using MTCO2 antibody (CAB17965) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
