The MT-CO2 Polyclonal Antibody (CAB11522) is a valuable tool for researchers studying the MT-CO2 protein, a subunit of cytochrome c oxidase involved in the electron transport chain within mitochondria. This antibody is produced in rabbits and exhibits high reactivity with human samples, making it ideal for use in Western blot applications.MT-CO2 is essential for the proper functioning of the electron transport chain, which is crucial for ATP production and cellular energy metabolism. Deregulation of MT-CO2 has been implicated in various diseases, including mitochondrial disorders and certain types of cancer. By targeting MT-CO2 with this antibody, researchers can gain insight into its expression levels and localization in different cell types, advancing our understanding of mitochondrial function and its role in health and disease.
The MT-CO2 Polyclonal Antibody is a valuable tool for investigating the role of MT-CO2 in mitochondrial function and cellular metabolism, with potential applications in studies related to energy production, oxidative stress, and disease pathology. Its specificity and sensitivity make it a reliable choice for researchers seeking to explore the intricate workings of the mitochondria and its impact on human health.
Product Name:
MTCO2 Rabbit Polyclonal Antibody
SKU:
CAB11522
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 101-200 of mouse MTCO2 (NP_904331.1).
Predicted to enable copper ion binding activity and oxidoreductase activity. Predicted to contribute to cytochrome-c oxidase activity. Predicted to be involved in ATP synthesis coupled electron transport; positive regulation of cellular biosynthetic process; and positive regulation of necrotic cell death. Located in mitochondrion. Is expressed in embryo; epiblast; heart; liver; and metanephros. Orthologous to several human genes including MTCO2P12 (MT-CO2 pseudogene 12).
Purification Method:
Affinity purification
Gene ID:
17709
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using MTCO2 Rabbit pAb (CAB11522) at 1:800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
