The MT-ATP8 Polyclonal Antibody (CAB17890) is a valuable tool for researchers studying mitochondrial ATP synthase subunit 8 (MT-ATP8), a key component of the electron transport chain in mitochondria. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.MT-ATP8 is essential for the synthesis of ATP, the energy currency of the cell, and its dysfunction has been linked to various mitochondrial disorders and diseases. By binding specifically to the MT-ATP8 protein, this antibody enables accurate detection and analysis of this crucial mitochondrial component in a variety of cell types.
Research into the role of MT-ATP8 in mitochondrial function and energy production is critical for understanding cellular metabolism and its impact on diseases such as neurodegenerative disorders, metabolic diseases, and cancer. The MT-ATP8 Polyclonal Antibody provides researchers with a reliable tool for investigating the function and regulation of MT-ATP8 in health and disease, making it a valuable asset in the fields of biochemistry and molecular biology.
Product Name:
MT-ATP8 Rabbit Polyclonal Antibody
SKU:
CAB17890
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-68 of human MT-ATP8 (YP_003024030.1).
mitochondrial inner membrane, mitochondrial proton-transporting ATP synthase complex, mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
Calculated MW:
8kDa
Observed MW:
12kDa
Contributes to proton-transporting ATP synthase activity, rotational mechanism. Involved in mitochondrial ATP synthesis coupled proton transport. Part of mitochondrial proton-transporting ATP synthase complex. Implicated in multiple sclerosis and urinary bladder cancer.
Purification Method:
Affinity purification
Gene ID:
4509
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using MT-ATP8 Rabbit pAb (CAB17890) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
