MSTN Rabbit Polyclonal Antibody (CAB6913)
- SKU:
- CAB6913
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MSTN Rabbit Polyclonal Antibody |
SKU: | CAB6913 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 267-375 of human GDF-8/Myostatin (NP_005250.1). |
Sequence: | DFGL DCDE HSTE SRCC RYPL TVDF EAFG WDWI IAPK RYKA NYCS GECE FVFL QKYP HTHL VHQA NPRG SAGP CCTP TKMS PINM LYFN GKEQ IIYG KIPA MVVD RCGC S |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:100 |
Synonyms: | GDF8; MSLHP; GDF-8/Myostatin |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 43kDa |
Observed MW: | 42kDa |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals.
Purification Method: | Affinity purification |
Gene ID: | 2660 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |