GDF-8/Myostatin Monoclonal Antibody (CAB22725)
- SKU:
- CAB22725
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | GDF-8/Myostatin Monoclonal Antibody |
SKU: | CAB22725 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-375 of human GDF-8/Myostatin(NP_005250.1). |
Sequence: | NENS EQKE NVEK EGLC NACT WRQN TKSS RIEA IKIQ ILSK LRLE TAPN ISKD VIRQ LLPK APPL RELI DQYD VQRD DSSD GSLE DDDY HATT ETII TMPT ESDF LMQV DGKP KCCF FKFS SKIQ YNKV VKAQ LWIY LRPV ETPT TVFV QILR LIKP MKDG TRYT GIRS LKLD MNPG TGIW QSID VKTV LQNW LKQP ESNL GIEI KALD ENGH DLAV TFPG PGED GLNP FLEV KVTD TPKR SRRD FGLD CDEH STES RCCR YPLT VDFE AFGW DWII APKR YKAN YCSG ECEF VFLQ KYPH THLV HQAN PRGS AGPC CTPT KMSP INML YFNG KEQI IYGK IPAM VVDR CGCS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | GDF8; MSLHP; GDF-8/Myostatin |
Positive Sample: | HeLa,Mouse skeletal muscle,Rat skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 43kDa |
Observed MW: | 50kDa |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals.
Purification Method: | Affinity purification |
Gene ID: | 2660 |
Clone Number: | ARC57469 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |