The MST1 Polyclonal Antibody (CAB12963) is a valuable tool for researchers studying the MST1 protein, an important regulator of cell apoptosis and inflammation. This antibody is raised in rabbits and is highly reactive with human samples, making it ideal for use in Western blot applications. The MST1 Polyclonal Antibody binds specifically to the MST1 protein, allowing for precise detection and analysis in various cell types.MST1, also known as mammalian sterile 20-like kinase 1, is involved in multiple cellular processes, including cell growth, differentiation, and survival. Dysregulation of MST1 has been implicated in various diseases, including cancer, cardiovascular disorders, and neurodegenerative conditions.
By studying the activity of MST1 using this antibody, researchers can gain insights into the mechanisms underlying these diseases and identify potential therapeutic targets.Overall, the MST1 Polyclonal Antibody is a valuable tool for scientists working in the fields of cell biology, cancer research, and inflammation. Its high reactivity and specificity make it a reliable choice for studying the function of MST1 and its implications in disease pathogenesis.
Product Name:
MSP/MST1 Rabbit Polyclonal Antibody
SKU:
CAB12963
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 200-500 of human MSP/MST1 (NP_066278.3).
The protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds.
Purification Method:
Affinity purification
Gene ID:
4485
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MSP/MST1 Rabbit pAb (CAB12963) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
