The MST1/STK4 Polyclonal Antibody is a valuable tool for researchers studying the MST1/STK4 protein, which plays key roles in signaling pathways related to apoptosis, cell cycle regulation, and immune responses. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for Western blot applications.MST1/STK4, also known as serine/threonine-protein kinase 4, is involved in regulating cell growth, survival, and differentiation, making it a promising target for investigating diseases such as cancer, autoimmune disorders, and inflammatory conditions.
By detecting and analyzing the MST1/STK4 protein in various cell types, researchers can gain insights into its function and potential therapeutic applications.Overall, the MST1/STK4 Polyclonal Antibody is a valuable tool for exploring the intricate mechanisms of cellular signaling pathways and advancing research in the fields of immunology, oncology, and molecular biology.
Product Name:
MST1/MST1/MST1/MST1/STK4 Polyclonal Antibody
SKU:
CAB21842
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 303-487 of human MST1 (NP_006273.1).
The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
Purification Method:
Affinity purification
Gene ID:
6789
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using MST1 Rabbit pAb (CAB21842) at1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
