The MSRB3 Polyclonal Antibody (CAB8005) is a valuable tool for researchers studying MSRB3, a protein involved in antioxidant defense mechanisms and cellular redox homeostasis. This antibody, generated in rabbits, specifically targets the MSRB3 protein and is suitable for use in various experimental techniques such as Western blotting.MSRB3, a member of the methionine sulfoxide reductase family, plays a crucial role in maintaining cellular oxidative balance and protecting against oxidative stress. Dysregulation of MSRB3 has been implicated in various diseases, including neurodegenerative disorders and cancer.
By utilizing the MSRB3 Polyclonal Antibody, researchers can investigate the function and expression of MSRB3 in different cell types and explore its potential as a therapeutic target.With its high specificity and sensitivity, the MSRB3 Polyclonal Antibody enables precise detection and quantification of MSRB3 levels, facilitating in-depth studies on the mechanisms underlying oxidative stress-related pathologies. This antibody is a valuable asset for investigators seeking to unravel the intricate role of MSRB3 in health and disease.
Product Name:
MSRB3 Rabbit Polyclonal Antibody
SKU:
CAB8005
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-185 of human MSRB3 (NP_001026849.1).
The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. Several transcript variants encoding two different isoforms have been found for this gene. One of the isoforms localizes to mitochondria while the other localizes to endoplasmic reticula.
Purification Method:
Affinity purification
Gene ID:
253827
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MSRB3 antibody (CAB8005) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
