The MSRA Polyclonal Antibody (CAB12464) is a valuable tool for researchers studying the methionine sulfoxide reductase A (MSRA) protein, which plays a key role in antioxidant defense mechanisms and protein repair processes. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications.MSRA is involved in the repair of oxidatively damaged proteins and is essential for cellular homeostasis and protection against oxidative stress. Dysregulation of MSRA has been linked to various diseases, including neurodegenerative disorders, cardiovascular conditions, and aging-related pathologies.
By targeting the MSRA protein, researchers can gain insights into the mechanisms underlying these diseases and potential therapeutic strategies.The MSRA Polyclonal Antibody enables the detection and analysis of MSRA expression in different cell types, making it a versatile tool for studies in the fields of biochemistry, molecular biology, and disease research. Its specificity and reliability make it an essential component in investigations aimed at understanding the functions and dysregulation of MSRA in health and disease.
Product Name:
MSRA Rabbit Polyclonal Antibody
SKU:
CAB12464
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-235 of human MSRA (NP_036463.1).
This gene encodes a ubiquitous and highly conserved protein that carries out the enzymatic reduction of methionine sulfoxide to methionine. Human and animal studies have shown the highest levels of expression in kidney and nervous tissue. The protein functions in the repair of oxidatively damaged proteins to restore biological activity. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
4482
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MSRA Antibody (CAB12464) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
