The MSN Polyclonal Antibody (CAB12473) is a valuable tool for researchers studying the MSN protein, which plays a key role in cell motility, adhesion, and signaling pathways. This antibody, generated in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blotting applications. By binding specifically to the MSN protein, this antibody allows for the detection and analysis of MSN expression in various cell types.MSN, also known as Moesin, is involved in cytoskeletal organization and cell morphology, making it a crucial protein in processes such as cell migration and invasion.
Dysregulation of MSN expression has been implicated in various diseases, including cancer and inflammatory disorders, highlighting the importance of studying this protein in a research context. The MSN Polyclonal Antibody enables researchers to further explore the role of MSN in disease progression and potential therapeutic interventions.
Product Name:
Moesin Rabbit Polyclonal Antibody
SKU:
CAB12473
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 458-557 of human Moesin (NP_002435.1).
Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement.
Purification Method:
Affinity purification
Gene ID:
4478
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Moesin antibody (CAB12473) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
