Msln Antibody (PACO28406)
- SKU:
- PACO28406
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Msln Antibody (PACO28406)
The MSLN Antibody (PACO28406) is a highly specific polyclonal antibody designed for research involving MSLN, a protein found on the cell surface of certain tissues, particularly in mesothelioma. This antibody, produced in rabbits, exhibits strong reactivity with human samples and is validated for use in various applications including immunohistochemistry and flow cytometry.MSLN, also known as mesothelin, is a potential biomarker and therapeutic target in cancer research due to its overexpression in various malignancies, including mesothelioma, ovarian cancer, and pancreatic cancer. The MSLN Antibody enables precise detection and analysis of MSLN protein expression in different cell types and tissues, making it an invaluable tool for studying the role of MSLN in cancer biology and the development of targeted therapies.
Research utilizing the MSLN Antibody can provide insights into the mechanisms of MSLN-associated tumorigenesis, metastasis, and drug resistance, offering potential avenues for the advancement of personalized medicine and improved treatment strategies for MSLN-positive cancers. Its high specificity and reliability make it an essential reagent for researchers seeking to deepen their understanding of MSLN biology and its implications in oncology.
| Antibody Name: | Msln Antibody (PACO28406) |
| Antibody SKU: | PACO28406 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse Mesothelin protein (298-600AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Membrane-anchored forms may play a role in cellular adhesion.Megakaryocyte-potentiating factor (MPF) may potentiate megakaryocyte colony formation. |
| Synonyms: | Mesothelin (Pre-pro-megakaryocyte-potentiating factor) [Cleaved into: Megakaryocyte-potentiating factor (MPF); Mesothelin, cleaved form], Msln, Mes Mpf |
| UniProt Protein Function: | MSLN: Membrane-anchored forms may play a role in cellular adhesion. Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer. Belongs to the mesothelin family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell adhesion; Membrane protein, GPI anchor Chromosomal Location of Human Ortholog: 17|17 A3.3 Cellular Component: cell surface; extracellular region; extracellular space; Golgi apparatus; membrane; plasma membrane Molecular Function:protein binding Biological Process: cell adhesion; cell-matrix adhesion |
| UniProt Code: | Q61468 |
| NCBI GenInfo Identifier: | 9256568 |
| NCBI Gene ID: | 56047 |
| NCBI Accession: | NP_061345.1 |
| UniProt Related Accession: | Q61468 |
| Molecular Weight: | |
| NCBI Full Name: | mesothelin preproprotein |
| NCBI Synonym Full Names: | mesothelin |
| NCBI Official Symbol: | Msln  |
| NCBI Official Synonym Symbols: | MPFÂ Â |
| NCBI Protein Information: | mesothelin |
| UniProt Protein Name: | Mesothelin |
| UniProt Synonym Protein Names: | Pre-pro-megakaryocyte-potentiating factor |
| Protein Family: | Mesothelin |
| UniProt Gene Name: | Msln  |
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