MSH4 Rabbit Polyclonal Antibody (CAB8556)
- SKU:
- CAB8556
- Product Type:
- Antibody
- Applications:
- WB
- IF
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MSH4 Rabbit Polyclonal Antibody |
SKU: | CAB8556 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 697-936 of human MSH4 (NP_002431.2). |
Sequence: | QIMA QIGS YVPA EYSS FRIA KQIF TRIS TDDD IETN SSTF MKEM KEIA YILH NAND KSLI LIDE LGRG TNTE EGIG ICYA VCEY LLSL KAFT LFAT HFLE LCHI DALY PNVE NMHF EVQH VKNT SRNK EAIL YTYK LSKG LTEE KNYG LKAA EVSS LPPS IVLD AKEI TTQI TRQI LQNQ RSTP EMER QRAV YHLA TRLV QTAR NSQL DPDS LRIY LSNL KKKY KEDF PRTE QVPE KTEE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ASG; POF20; SPGF2; MSH4 |
Positive Sample: | Mouse skeletal muscle,Rat skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | nucleus |
Calculated MW: | 105kDa |
Observed MW: | 105kDa |
This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair.
Purification Method: | Affinity purification |
Gene ID: | 4438 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |