MSH2 Rabbit Polyclonal Antibody (CAB1121)
- SKU:
- CAB1121
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | MSH2 Rabbit Polyclonal Antibody |
SKU: | CAB1121 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human MSH2 (NP_000242.1). |
Sequence: | MAVQ PKET LQLE SAAE VGFV RFFQ GMPE KPTT TVRL FDRG DFYT AHGE DALL AARE VFKT QGVI KYMG PAGA KNLQ SVVL SKMN FESF VKDL LLVR QYRV EVYK NRAG NKAS KEND WYLA YKAS PGNL SQFE DILF GNND MSAS IGVV GVKM SAVD GQRQ VGVG YVDS IQRK LGLC EFPD NDQF SNLE ALLI QIGP KECV LPGG ETAG DMGK LRQI IQRG GILI TERK KADF STKD IYQD LNRL LKGK KGEQ MNSA VLPE MENQ VAVS SLSA VIKF LELL SDDS NFGQ FELT TFDF SQYM |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | FCC1; COCA1; HNPCC; LCFS2; MSH-2; hMSH2; HNPCC1; LYNCH1; MMRCS2; MSH2 |
Positive Sample: | A-549,A-431,NIH/3T3 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 105kDa |
Observed MW: | 100kDa/105kDA |
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 4436 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |