The MS4A4A Polyclonal Antibody (PACO38170) is a valuable tool for researchers studying MS4A4A, a cell surface protein involved in immune regulation. Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding to the MS4A4A protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for studies in immunology and cancer research.MS4A4A, also known as a member of the membrane-spanning 4A family, plays a crucial role in regulating immune responses and inflammatory pathways.
Its involvement in immune function makes it a promising target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of MS4A4A is essential for developing potential therapies that can modulate immune responses in these disease contexts.Overall, the MS4A4A Polyclonal Antibody (PACO38170) is a reliable tool for scientists looking to study the role of MS4A4A in immune regulation and its potential implications in various disease states.
Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO38170 at dilution of 1:100.
Immunofluorescent analysis of MCF-7 cells using PACO38170 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
May be involved in signal transduction as a component of a multimeric receptor complex.
Synonyms:
Membrane-spanning 4-domains subfamily A member 4A (CD20 antigen-like 1) (Four-span transmembrane protein 1), MS4A4A, 4SPAN1 CD20L1 MS4A4
UniProt Protein Function:
MS4A4A: May be involved in signal transduction as a component of a multimeric receptor complex. Belongs to the MS4A family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 11q12
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features, similar intron/exon splice boundaries, and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
