The MS4A1 Polyclonal Antibody (CAB1793) is a valuable tool for researchers studying MS4A1, a member of the membrane-spanning 4A gene family. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the MS4A1 protein, this antibody allows for precise detection and analysis in various cell types, making it ideal for investigations in immunology and cancer research.MS4A1, also known as CD20, plays a crucial role in immune responses by regulating B cell activation and differentiation.
Its involvement in B cell signaling pathways makes it an important target for research on the development of therapies for autoimmune diseases, lymphomas, and other immune-related disorders. By gaining a better understanding of the function of MS4A1, researchers can work towards developing targeted treatments that modulate immune responses effectively.
Product Name:
CD20 Rabbit Polyclonal Antibody
SKU:
CAB1793
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 197-297 of human CD20 (NP_068769.2).
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein.
Purification Method:
Affinity purification
Gene ID:
931
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from Raji cells, using CD20 Rabbit pAb (CAB1793) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
