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MRRF Monoclonal Antibody [PAT7D10A] (CPAB0461)

SKU:
CPAB0461
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT7D10A
Applications:
WB
ELISA
€149

Description

system_update_alt Datasheet

MRRF Monoclonal Antibody [PAT7D10A] (CPAB0461)

The MRRF Antibody (CPAB0461) is a polyclonal antibody designed for research involving MRRF, a protein associated with mitochondrial ribosome biogenesis. This antibody, raised in rabbits, is highly reactive with MRRF in human samples and has been validated for use in Western blot applications. By binding specifically to MRRF, this antibody enables the detection and analysis of this protein in various cell types, making it an ideal tool for studies in mitochondrial biology and ribosome biogenesis.MRRF plays a critical role in the assembly and function of the mitochondrial ribosome, which is essential for proper cellular energy production.

Dysregulation of MRRF has been linked to mitochondrial dysfunction and may contribute to various diseases, including metabolic disorders and neurodegenerative diseases. Understanding the function of MRRF is crucial for unraveling the mechanisms of mitochondrial biogenesis and its implications for human health.Overall, the MRRF Antibody (CPAB0461) provides researchers with a reliable tool for investigating the role of MRRF in mitochondrial ribosome biogenesis and its potential impact on cellular function and disease pathology.

Product Name:MRRF Antibody
Product Sku:CPAB0461
Size:5μg
Host Species:Mouse
Immunogen:Anti-human MRRF mAb, clone PAT7D1A, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human MRRF protein 56-262 amino acids  purified from Ecoli.
Clone:PAT7D10A.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:MRRF antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:Mitochondrial Ribosome Recycling Factor (MRRF) is a member of the RRF family. MRRF attaches to the large ribosomal subunit in the cleft which has a peptidyl transferase center. MRRF controls the release of ribosome from messenger RNA at the termination of protein biosynthesis. Also, it may intensify the efficacy of translation by recycling ribosome from one round of translation to another.
Synonyms:MRFF, MTRRF, RRF, Ribosome-recycling factor, mitochondrial, Ribosome-releasing factor, mitochondrial.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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