The MRPS7 Polyclonal Antibody (CAB17150) is a valuable tool for researchers studying MRPS7, a mitochondrial ribosomal protein involved in protein synthesis within the mitochondria. This rabbit-raised antibody is highly specific and reactive with human samples, making it ideal for use in Western blot applications to detect and analyze MRPS7 protein levels in various cell types.MRPS7 plays a crucial role in mitochondrial function and protein synthesis, making it an important target for studies in mitochondrial biology, metabolism, and diseases related to mitochondrial dysfunction.
By understanding the role of MRPS7 in cellular processes, researchers can gain insights into diseases such as metabolic disorders, neurodegenerative diseases, and cancer, where mitochondrial dysfunction plays a significant role.With its high specificity and reliability, the MRPS7 Polyclonal Antibody (CAB17150) is a valuable tool for researchers looking to explore the role of MRPS7 in health and disease, providing insights that can potentially lead to the development of targeted therapies and diagnostic tools.
Product Name:
MRPS7 Rabbit Polyclonal Antibody
SKU:
CAB17150
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 110-190 of human MRPS7 (NP_057055.2).
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. In the prokaryotic ribosome, the comparable protein is thought to play an essential role in organizing the 3' domain of the 16 S rRNA in the vicinity of the P- and A-sites. Pseudogenes corresponding to this gene are found on chromosomes 8p and 12p.
Purification Method:
Affinity purification
Gene ID:
51081
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MRPS7 Rabbit pAb (CAB17150) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
