MRPS5 Antibody (PACO28386)
- SKU:
- PACO28386
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
MRPS5 Antibody (PACO28386)
The MRPS5 Polyclonal Antibody (PAC028386) is a valuable tool for researchers studying MRPS5, a key protein involved in mitochondrial ribosome biogenesis. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, and has been validated for Western blot applications. By binding to the MRPS5 protein, it allows for accurate detection and analysis in a variety of cell types, making it an essential component for studies in mitochondrial biology and related fields.MRPS5, also known as Mitochondrial Ribosomal Protein S5, plays a crucial role in the assembly of the mitochondrial ribosome, which is essential for protein synthesis within the mitochondria.
Dysregulation of MRPS5 has been implicated in various diseases, including mitochondrial disorders and cancer. Therefore, understanding the function and regulation of MRPS5 is essential for advancing our knowledge of mitochondrial biology and exploring potential therapeutic targets for related diseases. Overall, the MRPS5 Polyclonal Antibody offers researchers a reliable tool for exploring the role of MRPS5 in cellular processes, providing valuable insights into mitochondrial function and its implications for human health.
| Antibody Name: | MRPS5 Antibody (PACO28386) |
| Antibody SKU: | PACO28386 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human 28S ribosomal protein S5, mitochondrial protein (161-430AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: MRPS5 antibody at 5µg/ml Lane 1: Hela whole cell lysate Lane 2: Jurkat whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 49, 28 kDa Observed band size: 49 kDa . |
| Background: | mitochondrial inner membrane, mitochondrial small ribosomal subunit, mitochondrion, poly(A) RNA binding, structural constituent of ribosome, mitochondrial translation, mitochondrial translational elongation, mitochondrial translational initiation, mitochondrial translational termination, organelle organization |
| Synonyms: | 28S ribosomal protein S5, mitochondrial (MRP-S5) (S5mt) (Mitochondrial small ribosomal subunit protein uS5m), MRPS5 |
| UniProt Protein Function: | MRPS5: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S5P family. Pseudogenes corresponding to this gene are found on chromosomes 4q, 5q, and 18q. [provided by RefSeq, Jul 2008]Protein type: RNA-bindingChromosomal Location of Human Ortholog: 2p11.2-q11.2Cellular Component: mitochondrion; mitochondrial small ribosomal subunit; mitochondrial inner membraneMolecular Function: structural constituent of ribosomeBiological Process: mitochondrial translation; translation; organelle organization and biogenesis |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P82675 |
| NCBI GenInfo Identifier: | 13994259 |
| NCBI Gene ID: | 64969 |
| NCBI Accession: | NP_114108 |
| UniProt Secondary Accession: | P82675 |
| UniProt Related Accession: | P82675 |
| Molecular Weight: | 47kDa |
| NCBI Full Name: | |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | 28S ribosomal protein S5, mitochondrial |
| UniProt Synonym Protein Names: | |
| Protein Family: | 28S ribosomal protein |
| UniProt Gene Name: | MRPS5Â Â |
| UniProt Entry Name: | RT05_HUMAN |
| Antibodies |
| MRPS5 Antibody (PACO05068) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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