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MRPS5 Antibody (PACO22421)

SKU:
PACO22421
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€419
Frequently bought together:

Description

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MRPS5 Antibody (PACO22421)

The MRPS5 Monoclonal Antibody (PACO22421) is a valuable tool for researchers investigating mitochondrial ribosomal protein S5, a key player in mitochondrial protein synthesis and cellular respiration. This antibody, developed using hybridoma technology, specifically targets the MRPS5 protein in human samples and is validated for use in various applications, including immunofluorescence and flow cytometry.MRPS5 is essential for proper functioning of the mitochondria, the powerhouse of the cell, and its dysregulation has been implicated in various diseases, including metabolic disorders and cancer.

By detecting and analyzing MRPS5 expression, researchers can gain insights into mitochondrial function and its role in disease development. This antibody is ideal for studies in cell biology, metabolism, and mitochondrial research, providing a deeper understanding of the molecular mechanisms underlying these processes.

Antibody Name:MRPS5 Antibody (PACO22421)
Antibody SKU:PACO22421
Size:100ul
Host Species:Rabbit
Tested Applications:ELISA, IHC
Recommended Dilutions:ELISA:1:2000-1:10000, IHC:1:50-1:100
Species Reactivity:Human
Immunogen:Synthesized peptide derived from internal of human MRPS5.
Form:Liquid
Storage Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageImmunohistochemistry analysis of paraffin-embedded human testis tissue using MRPS5 antibody.
Background:Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S5P family. Pseudogenes corresponding to this gene are found on chromosomes 4q, 5q, and 18q.
Synonyms:Mitochondrial 28S ribosomal protein S5; S5mt; MRP-S5;
UniProt Protein Function:MRPS5: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S5P family. Pseudogenes corresponding to this gene are found on chromosomes 4q, 5q, and 18q. [provided by RefSeq, Jul 2008]Protein type: RNA-bindingChromosomal Location of Human Ortholog: 2p11.2-q11.2Cellular Component: mitochondrion; mitochondrial small ribosomal subunit; mitochondrial inner membraneMolecular Function: structural constituent of ribosomeBiological Process: mitochondrial translation; translation; organelle organization and biogenesis
UniProt Protein Details:
NCBI Summary:
UniProt Code:P82675
NCBI GenInfo Identifier:13994259
NCBI Gene ID:64969
NCBI Accession:NP_114108
UniProt Secondary Accession:P82675
UniProt Related Accession:P82675
Molecular Weight:47kDa
NCBI Full Name:
NCBI Synonym Full Names:
NCBI Official Symbol:
NCBI Official Synonym Symbols:
NCBI Protein Information:
UniProt Protein Name:28S ribosomal protein S5, mitochondrial
UniProt Synonym Protein Names:
Protein Family:28S ribosomal protein
UniProt Gene Name:MRPS5  
UniProt Entry Name:RT05_HUMAN
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