The MRPS5 Polyclonal Antibody (PACO05068) is specifically designed for research involving the MRPS5 protein, a vital component of the mitochondrial ribosome involved in protein synthesis. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in various applications, including Western blotting and immunohistochemistry.The MRPS5 protein plays a crucial role in maintaining mitochondrial function and energy production, making it an essential target for studies related to mitochondrial biology, cell metabolism, and diseases associated with mitochondrial dysfunction. By detecting and analyzing the MRPS5 protein in different cell types, this antibody is a valuable tool for researchers in the fields of biochemistry, cell biology, and mitochondrial research.
Understanding the function and regulation of MRPS5 is key to unraveling the mechanisms underlying mitochondrial dysfunction and its implications in various diseases, such as neurodegenerative disorders, metabolic diseases, and cancer. By using the MRPS5 Polyclonal Antibody, researchers can gain valuable insights into the role of MRPS5 in cellular processes and potentially uncover new therapeutic targets for treating mitochondrial-related conditions.
Antibody Name:
MRPS5 Antibody (PACO05068)
Antibody SKU:
PACO05068
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:40000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the C-terminal region of human MRP-S5.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
MRPS5; 28S ribosomal protein S5; mitochondrial; MRP-S5; S5mt
UniProt Protein Function:
MRPS5: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S5P family. Pseudogenes corresponding to this gene are found on chromosomes 4q, 5q, and 18q. [provided by RefSeq, Jul 2008]Protein type: RNA-bindingChromosomal Location of Human Ortholog: 2p11.2-q11.2Cellular Component: mitochondrion; mitochondrial small ribosomal subunit; mitochondrial inner membraneMolecular Function: structural constituent of ribosomeBiological Process: mitochondrial translation; translation; organelle organization and biogenesis
