The MRPS36 Polyclonal Antibody (PAC028382) is a specialized antibody designed for research involving the mitochondrial ribosomal protein S36 (MRPS36). This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the MRPS36 protein, this antibody enables accurate detection and analysis in various cell types, making it an essential tool for studies in mitochondrial biology and related fields.MRPS36 is a vital component of the mitochondrial ribosome, playing a crucial role in protein synthesis within the mitochondria. Dysfunction in mitochondrial ribosomal proteins like MRPS36 has been linked to various diseases, including metabolic disorders, neurodegenerative conditions, and cancer.
Understanding the function and regulation of MRPS36 is essential for unraveling the molecular mechanisms underlying these diseases and developing potential therapeutic interventions.The MRPS36 Polyclonal Antibody serves as a valuable instrument for researchers exploring the role of MRPS36 in mitochondrial function, protein synthesis, and disease pathogenesis. Its high specificity and sensitivity make it an indispensable tool for uncovering new insights into mitochondrial biology and its implications for human health.
Antibody Name:
MRPS36 Antibody (PACO28382)
Antibody SKU:
PACO28382
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human 28S ribosomal protein S36, mitochondrial protein (1-103AA)
28S ribosomal protein S36, mitochondrial (MRP-S36) (S36mt), MRPS36
UniProt Protein Function:
MRPS36: Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.Protein type: Mitochondrial; Translation; RibosomalChromosomal Location of Human Ortholog: 5q13.2Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial small ribosomal subunitMolecular Function: structural constituent of ribosomeBiological Process: translation; mitochondrial translation; organelle organization and biogenesis
UniProt Protein Details:
NCBI Summary:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. The mitochondrial ribosome (mitoribosome) consists of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 3p, 4q, 8p, 11q, 12q, and 20p. [provided by RefSeq, Jul 2008]
