Anti-MRPS36 Antibody (PACO23448)

Antibody Name:	MRPS36 Antibody (PACO23448)
Antibody SKU:	PACO23448
Size:	100ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100
Species Reactivity:	Human
Immunogen:	Synthesized peptide derived from internal of human MRPS36.

Form:	Liquid
Storage Buffer:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Western blot analysis of extracts from HepG2 cells, using MRPS36 antibody.
	Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using MRPS36 antibody.

Background:

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. The mitochondrial ribosome (mitoribosome) consists of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 3p, 4q, 8p, 11q, 12q, and 20p.

Synonyms:

DC47; mitochondrial 28S ribosomal protein S36; MRP-S36; RT36; S36mt

UniProt Protein Function:	MRPS36: Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.Protein type: Mitochondrial; Translation; RibosomalChromosomal Location of Human Ortholog: 5q13.2Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial small ribosomal subunitMolecular Function: structural constituent of ribosomeBiological Process: translation; mitochondrial translation; organelle organization and biogenesis
UniProt Protein Details:
NCBI Summary:	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. The mitochondrial ribosome (mitoribosome) consists of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 3p, 4q, 8p, 11q, 12q, and 20p. [provided by RefSeq, Jul 2008]
UniProt Code:	P82909
NCBI GenInfo Identifier:	15150811
NCBI Gene ID:	92259
NCBI Accession:	NP_150597.1
UniProt Secondary Accession:	P82909,Q9H2H4
UniProt Related Accession:	P82909
Molecular Weight:	11,466 Da
NCBI Full Name:	28S ribosomal protein S36, mitochondrial
NCBI Synonym Full Names:	mitochondrial ribosomal protein S36
NCBI Official Symbol:	MRPS36
NCBI Official Synonym Symbols:	DC47; MRP-S36
NCBI Protein Information:	28S ribosomal protein S36, mitochondrial
UniProt Protein Name:	28S ribosomal protein S36, mitochondrial
UniProt Synonym Protein Names:
Protein Family:	28S ribosomal protein
UniProt Gene Name:	MRPS36
UniProt Entry Name:	RT36_HUMAN

Antibodies

MRPS36 Antibody (PACO01109)

MRPS36 Antibody (PACO10616)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)