The MRPS36 Polyclonal Antibody (PAC010616) is a valuable tool for researchers studying mitochondrial ribosomal protein S36 (MRPS36), a critical component of the mitochondrial ribosome involved in protein synthesis. This antibody is produced in rabbits and has been validated for use in various research applications, including Western blotting and immunofluorescence.MRPS36 plays a crucial role in maintaining mitochondrial function and energy production, making it a key target for investigation in studies relating to mitochondrial dysfunction, metabolic diseases, and neurodegenerative disorders.
By targeting MRPS36 with this antibody, researchers can effectively detect and analyze the protein in different cell types, providing valuable insights into its function and potential therapeutic implications.The high reactivity of the MRPS36 Polyclonal Antibody with human samples makes it an ideal choice for researchers looking to explore the role of MRPS36 in disease pathways and identify novel therapeutic targets. With its specificity and sensitivity, this antibody offers a reliable tool for advancing research in the fields of biochemistry, cell biology, and molecular biology.
mitochondrial ribosomal protein S36;MRPS36;DC47;MGC22896;MRP-S36 ;
UniProt Protein Function:
MRPS36: Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.Protein type: Mitochondrial; Translation; RibosomalChromosomal Location of Human Ortholog: 5q13.2Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial small ribosomal subunitMolecular Function: structural constituent of ribosomeBiological Process: translation; mitochondrial translation; organelle organization and biogenesis
UniProt Protein Details:
NCBI Summary:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. The mitochondrial ribosome (mitoribosome) consists of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 3p, 4q, 8p, 11q, 12q, and 20p. [provided by RefSeq, Jul 2008]
