The MRPS36 Polyclonal Antibody (PAC01109) is a valuable tool for researchers studying the mitochondrial ribosomal protein S36 (MRPS36) and its role in cellular function. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By binding to the MRPS36 protein, this antibody enables the detection and analysis of MRPS36 in various cell types, making it ideal for studies in mitochondrial biology and related fields.MRPS36 is a crucial component of the mitochondrial ribosome, playing a vital role in protein synthesis within the mitochondria.
Dysregulation of MRPS36 has been linked to various mitochondrial disorders and diseases, making it a target of interest for researchers in the fields of genetics, neurobiology, and metabolism. Understanding the function and regulation of MRPS36 is essential for developing targeted therapies for mitochondrial-related conditions.Overall, the MRPS36 Polyclonal Antibody (PAC01109) offers researchers a reliable tool for investigating the role of MRPS36 in mitochondrial protein synthesis and its implications in human health and disease.
Antibody Name:
MRPS36 Antibody
Antibody SKU:
PACO01109
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the N-terminal region of human MRP-S36.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
MRPS36; DC47; 28S ribosomal protein S36; mitochondrial; MRP-S36; S36mt
UniProt Protein Function:
MRPS36: Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.Protein type: Mitochondrial; Translation; RibosomalChromosomal Location of Human Ortholog: 5q13.2Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial small ribosomal subunitMolecular Function: structural constituent of ribosomeBiological Process: translation; mitochondrial translation; organelle organization and biogenesis
UniProt Protein Details:
NCBI Summary:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. The mitochondrial ribosome (mitoribosome) consists of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 3p, 4q, 8p, 11q, 12q, and 20p. [provided by RefSeq, Jul 2008]
