The MRPS34 Polyclonal Antibody (PACO06657) is a valuable tool for researchers studying MRPS34, a mitochondrial ribosomal protein implicated in mitochondrial protein synthesis and cellular energy production. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the MRPS34 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it ideal for investigations in mitochondrial biology and metabolic research.MRPS34, a key component of the mitochondrial ribosome, plays a crucial role in the translation of mitochondrial DNA-encoded proteins essential for oxidative phosphorylation and ATP production.
Disruptions in MRPS34 function have been linked to mitochondrial dysfunction and metabolic disorders, highlighting the importance of studying this protein in the context of cellular energy metabolism. The MRPS34 Polyclonal Antibody provides researchers with a valuable tool for exploring the role of MRPS34 in mitochondrial function and its implications for human health.
Antibody Name:
MRPS34 Antibody (PACO06657)
Antibody SKU:
PACO06657
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:10000, WB:1:500-1:2000
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from the C-terminal region of human MRP-S34.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western Blot analysis of Jurkat HuvEc cells using MRP-S34 Polyclonal Antibody.
Western Blot analysis of Jurkat cells using MRP-S34 Polyclonal Antibody.
Synonyms:
MRPS34; 28S ribosomal protein S34; mitochondrial; MRP-S34; S34mt
UniProt Protein Function:
MRPS34: Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.Chromosomal Location of Human Ortholog: 16p13.3Cellular Component: mitochondrial inner membrane; mitochondrionBiological Process: mitochondrial translation
UniProt Protein Details:
NCBI Summary:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
