MRPS31 Rabbit Polyclonal Antibody (CAB12923)
- SKU:
- CAB12923
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | MRPS31 Rabbit Polyclonal Antibody |
SKU: | CAB12923 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 66-395 of human MRPS31 (NP_005821.2). |
Sequence: | ICSK KDKQ SVRT EETS KETS ESQD SEKE NTKK DLLG IIKG MKVE LSTV NVRT TKPP KRRP LKSL EATL GRLR RATE YAPK KRIE PLSP ELVA AASA VADS LPFD KQTT KSEL LSQL QQHE EESR AQRD AKRP KISF SNII SDMK VARS ATAR VRSR PELR IQFD EGYD NYPG QEKT DDLK KRKN IFTG KRLN IFDM MAVT KEAP ETDT SPSL WDVE FAKQ LATV NEQP LQNG FEEL IQWT KEGK LWEF PINN EAGF DDDG SEFH EHIF LEKH LESF PKQG PIRH FMEL VTCG LSKN PYLS VKQK VEHI EWFR NYFN EKKD ILKE SNIQ FN |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | S31mt; IMOGN38; MRP-S31; MRPS31 |
Positive Sample: | Jurkat,HeLa,HepG2,MCF7,A-431 |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion. |
Calculated MW: | 45kDa |
Observed MW: | 37kDa |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that has also been associated with type 1 diabetes; however, its relationship to the etiology of this disease remains to be clarified. Pseudogenes corresponding to this gene have been found on chromosomes 3 and 13.
Purification Method: | Affinity purification |
Gene ID: | 10240 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |