The MRPS10 Monoclonal Antibody (PACO10596) is a valuable tool for research projects focused on mitochondrial ribosomal protein S10 (MRPS10). This antibody, produced through hybridoma technology, exhibits high specificity and sensitivity in detecting MRPS10 in human samples, making it an ideal choice for various experimental techniques, including Western blotting and immunohistochemistry.MRPS10 is a crucial component of the mitochondrial ribosome and plays a vital role in protein synthesis within the mitochondria. Dysregulation of MRPS10 has been associated with mitochondrial dysfunction and various diseases, including cancer and neurodegenerative disorders.
Researchers interested in exploring the role of MRPS10 in these conditions will find this antibody essential for their studies.By utilizing the MRPS10 Monoclonal Antibody (PACO10596), scientists can gain insights into the functions of MRPS10 and its involvement in mitochondrial biology and disease pathology. This antibody offers a reliable and specific tool for investigating the potential therapeutic targets and pathways associated with MRPS10, facilitating advancements in biomedical research and drug development.
mitochondrial ribosomal protein S10;MRPS10;FLJ10567;MRP-S10;PNAS-122 ;
UniProt Protein Function:
MRPS10: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S10P family. Pseudogenes corresponding to this gene are found on chromosomes 1q, 3p, and 9p. [provided by RefSeq, Jul 2008]Protein type: MitochondrialChromosomal Location of Human Ortholog: 6p21.1Cellular Component: mitochondrial inner membrane; mitochondrionBiological Process: positive regulation of defense response to virus by host
UniProt Protein Details:
NCBI Summary:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S10P family. Pseudogenes corresponding to this gene are found on chromosomes 1q, 3p, and 9p. [provided by RefSeq, Jul 2008]
